One civilization will aim to find a new home for all life forms in another galaxy before the death of this one.
To do this, they will need to find a way to travel faster than the speed of light.
This may be possible through the use of wormholes.
I doubt if humans will survive till that time. New life forms / super-humans may get this challenge to solve.
Till then, all we need is to avoid nuclear armageddon.
Photo by Kristopher Roller on Unsplash